Crystallographers identify 1,000 protein structures

The Canadian Light Source is celebrating two milestones reached by scientists

… who have conducted research at the national facility at the University of Saskatchewan. Scientists have solved 1,000 protein structures using data collected at CLS’s CMCF beamlines. These have been added to the Protein Data Bank – a collection of structures solved by researchers globally. Researchers have also published 500 scientific papers based on their work using the crystallography beamlines.

Proteins are the building blocks of life and are described as the body’s workhorses. The body is made of trillions of cells. Cells produce proteins, which do the work of breaking down food, sending messages to other cells, and fighting bacteria, viruses and parasites. The discoveries at the CLS range from how the malaria parasite invades red blood cells to why superbugs are resistant to certain antibiotics and how parkin protein mutations result in some types of Parkinson’s disease. Understanding how these and other such proteins work can potentially save millions of lives.

“Each of these protein structures that have been solved at the CLS represents a significant contribution to the global body of knowledge in the areas of biology and biochemistry, advancing health research,” says CEO Rob Lamb.