This is the first users’ meeting after the COVID-19 pandemic and will give a chance to highlight the experimental activities at the three operational beamlines (IR, XAFS/XRF and MSXPD) together with the status of the two new BEATS and HESEB beamlines. Present and future SESAME users are warmly invited to participate in the selection by presenting their work and ideas for future use of SESAME and by meeting on-site for discussion, interaction and networking.