The Multimode InfraRed Imaging And Microspectroscopy (MIRIAM) Beamline B22, is a state-of-the-art IR facility, providing the highest spatial resolution and molecular sensitivity optically attainable over the full IR range, including THz. B22 is highly multidisciplinary with experiments that involve biomedicine, materials science, chemistry, geology, space science and cultural heritage.
MIRIAM has pioneered the development of full-field IR hyperspectral imaging using Focal Plane Array (FPA) detection with Synchrotron Radiation (SR) illumination. The development of FPA-SR has provided a new frontier in live-cell imaging where molecular changes in cellular machinery can be monitored over time (Quaroni et al. Faraday Discussions 2015 DOI:10.1039/C5FD00156K). Furthermore, the combination of high magnification (36x or 74x) objectives and SR illumination enables rapid IR full-field microscopy in high-definition with significant image oversampling. This IR molecular imaging can reveal sub-cellular structures in both prokaryotic and eukaryotic cells, or micro-features in composite/meta-materials.
B22 is recruiting a Post-Doctoral Research Associate for primary research in full-field IR microscopy via FPA detector and Synchrotron IR illumination. The research will develop fast molecular imaging capabilities to be applied to the wide range of scientific problems investigated by IR microspectroscopy at B22. The Diamond position will be based at the MIRIAM Beamline B22 with research, in collaboration with the Department of Engineering Science at Oxford University.
The experimental project is focused on a novel use of adaptive optics, to produce high-contrast IR images and high signal-to-noise spectra at every pixel of the FPA detector. The hardware and control system – already implemented at MIRIAM beamline – makes use of an innovative double set of deformable mirrors for shaping the IR beam profile. The software part of the project, in collaboration with Prof. Martin Booth – a leader in the field of adaptive optics for super-resolution visible microscopy at Oxford University – will develop open and closed loop algorithms for fully optimizing the IR illumination for the highest throughput and homogenous illumination at the sample plane.
Suitable candidates should be familiar with spectroscopy and microscopy techniques, preferentially IR or vibrational imaging/microscopy. Following full commissioning of the adaptive optics system, the post also provides the opportunity for the successful candidate to develop their own research focus, which would ideally benefit from the application of the IR imaging system via FPA detector and SR illumination. Moreover, the position will offer opportunities to participate in user experiments at B22, which cover a wide variety of disciplines, as well as, working in collaboration with external users and beamline staff for in-house experiments.
Where appropriate for the role, we will consider flexible working arrangements and secondment opportunities (e.g. for fixed-term contract positions).
Diamond are members of the Employers Network for Equality & Inclusion and we have achieved the Athena SWAN Bronze award and Disability Confident Level One. Women are underrepresented and so we particularly welcome applications from suitably qualified women. If you are disabled and would like to be considered under the Guaranteed Interview Scheme, please let us know via the online application process.
To apply for this job please visit vacancies.diamond.ac.uk.