Beamline I04-1 is part of Diamond’s Macromolecular Crystallography (MX) Village, optimised for routine and high throughput cryogenic data collection. It hosts users of the regular MX user programme, while its fast unattended queued operation crucially underpins the XChem programme. We are looking for a crystallographer who will help the Beamline and the MX Village adapt the user programme to the rapidly evolving needs of the user community, in particular remote and unattended access. The person will also help achieve Beamline upgrades including smaller beam sizes, improved accuracy, faster detectors, and higher beam flux, that will make it possible to screen currently problematic crystal systems such as membrane proteins or larger protein-protein complexes. This work includes Beamline preparation for the Diamond II upgrade due in the next decade.
The person will also work closely with the XChem facility, developed in partnership with the SGC-Oxford, which now routinely hosts users every week, and in 2017 measured over 35,000 crystals in academic and industrial experiments. Through collaborations or own interests, the person will be involved in projects addressing the post-screening next bottleneck, namely converting low potency fragments into high-potency compounds leading to probes or drug leads.
Where appropriate for the role, we will consider flexible working arrangements and secondment opportunities (e.g. for fixed-term contract positions).
Diamond are members of the Employers Network for Equality & Inclusion and we have achieved the Athena SWAN Bronze award and Disability Confident Level One. Women are underrepresented and so we particularly welcome applications from suitably qualified women. If you are disabled and would like to be considered under the Guaranteed Interview Scheme, please let us know via the online application process.
To apply for this job please visit vacancies.diamond.ac.uk.