… and other modern drugs.
Researchers from McGill University and Yale University used the Canadian Light Source (CLS) at the University of Saskatchewan to make a discovery that could help design future therapeutic drugs. The research team studied how mega-enzymes, known as nonribosomal peptide synthetases (NRPSs), create potent antibiotics, immunosuppressants and other modern drugs.
In a paper featured on the cover of the May 2020 issue of Nature Chemical Biology, the team reports how they were able to visualize an NRPSs’ mechanical system using the CMCF beamline at the CLS.
Image: Associate Professor Schmeing in the lab