Cosmic dust could have sparked life on Earth

New research has found that amino acids, the building blocks of life, may have travelled to Earth on interstellar dust grains, potentially helping kickstart biology as we know it.

In a recent study published in the Monthly Notices of the Royal Astronomical Society, Stephen Thompson, I11’s principal beamline scientist, and Sarah Day, I11 beamline scientist, explored how amino acids like glycine and alanine could survive the harsh conditions of space and make their way to Earth embedded in cosmic dust.  

Amino acids are the molecular foundations of proteins and enzymes, which drive every biological process in living organisms. While scientists have long debated whether these molecules formed on Earth or arrived from space, this new study offers compelling evidence that cosmic dust may have played a crucial role in delivering them. The team synthesised tiny particles of amorphous magnesium silicate, a major component of cosmic dust, and deposited amino acids – glycine, alanine, glutamic acid, and aspartic acid – onto them. Using infrared spectroscopy and synchrotron X-ray powder diffraction, they then examined how these molecules behaved when the silicate particles were heated, simulating the warming that occurs as dust grains travelled through the early solar system. 

They found that only glycine and alanine successfully adhered to the silicate particles. These amino acids formed crystalline structures and in the case of alanine remained stable at temperatures well above its melting point. The study also found that the two mirror-image forms of alanine (L- and D-alanine) behaved differently under heating, with L-alanine showing more reactivity than its D-form. Glycine, on the other hand, was lost from the silicate at temperatures lower than its pure decomposition point, indicating that it detached from the grain surface rather than breaking down.  

The team prepared two batches of amorphous silicate and subjected one batch to heat treatment prior to depositing the amino acids. This was to remove hydrogen atoms from the silicate surface, producing two silicates with differing surface properties, which were also found to influence the temperatures at which the amino acids were lost.    

These subtle differences may have had profound implications for the types of molecules that seeded life on Earth. 

Read more on the Diamond website

Image: Stephen Thompson, I11’s principal beamline scientist, and Sarah Day, I11 beamline scientist, working on their cosmic dust research

Credit: Diamond Light Source   

Unravelling tautomeric mixtures

RIXS at BESSY II allows to see clearly

A team at HZB has developed a method of experimentally unravelling tautomeric mixtures. Based on resonant inelastic X-ray scattering (RIXS) at BESSY II, not only proportions of the tautomers can be deduced, but the properties of each individual tautomer can be studied selectively. This method could yield to detailed information on the properties of molecules and their biological function. In the present study, now advertised on the cover of “The Journal of Physical Chemistry Letters” the technique was applied to the prototypical keto-enol equilibrium.

Many (organic) molecules exist as a mixture of two almost identical molecules, with the same molecular formula but one important difference: A single hydrogen atom sits in a different position. The two isomeric forms transform into each other, creating a delicate equilibrium, a “tautomeric” mixture. Many amino acids are tautomeric mixtures, and since they are building blocks of proteins, they may influence their shape and function and thus their biological functions in organisms.

Until now: Mission impossible

Until now, it has been impossible to selectively investigate the electronic structure of such tautomeric mixtures experimentally: Classical spectroscopic methods “see” only the sum of the signals of each molecular forms – the details of the properties of the two individual tautomers cannot be determined.

Now at BESSY II: it works

A team led by HZB physicist Prof. Alexander Föhlisch has now succeeded in providing a method of experimentally unravelling tautomeric mixtures. Using inelastic X-ray scattering (RIXS) and a data processing/evaluation method newly developed at HZB, the individual proportions of the tautomers can be clearly deduced from the measured data. “We can experimentally separate the signal of each individual molecule in the mixture by X-ray scattering, which leads to a detailed insight into their functionality and chemical properties,” says Dr. Vinicíus Vaz Da Cruz, first author of the paper and postdoc in Föhlisch’s team.

Read more on the HZB website

Image: The illustration visualises the experimental method, here on the prototypical keto-enol equilibrium. It appears on the cover of “The Journal of Physical Chemistry Letters”.

Credit: © Martin Künsting / HZB